منابع مشابه
Control of oxidative phosphorylation in muscle.
There is no single answer to the question ‘How is oxidative phosphorylation controlled (or regulated)?’. Control varies with conditions, and is shared between at least two different reactions under all conditions. However, it is possible to provide a simple quantitative description of the control using control analysis. Hecause of the kinetics of all three blocks of reactions involved, oxidatio...
متن کاملControl of oxidative phosphorylation during insect metamorphosis.
The midgut of the tobacco hornworm (Manduca sexta) is a highly aerobic tissue that is destroyed and replaced by a pupal epithelium at metamorphosis. To determine how oxidative phosphorylation is altered during the programmed death of the larval cells, top-down control analysis was performed on mitochondria isolated from the midguts of larvae before and after the commitment to pupation. Oxygen c...
متن کاملControl mechanisms in mitochondrial oxidative phosphorylation☆
Distribution and activity of mitochondria are key factors in neuronal development, synaptic plasticity and axogenesis. The majority of energy sources, necessary for cellular functions, originate from oxidative phosphorylation located in the inner mitochondrial membrane. The adenosine-5'- triphosphate production is regulated by many control mechanism-firstly by oxygen, substrate level, adenosine...
متن کاملGenetic control of oxidative phosphorylation and experimental models of defects.
Energy in the form of ATP is continually produced by all cells for normal growth and function. Anaerobic glycolysis can provide enough ATP for some cells, but energetic cells such as cardiomyocytes and neurons require a more efficient ATP supply, which can only be provided by mitochondrial oxidative phosphorylation. Invented by bacteria that became symbiotically associated with other bacteria t...
متن کاملTop-down control analysis of temperature effect on oxidative phosphorylation.
The effects of temperature on the control of respiration rate, phosphorylation rate, proton leakage rate, the protonmotive force and the effective ATP/O ratio were determined in isolated rat liver mitochondria over a range of respiratory conditions by applying top-down elasticity and control analyses. Simultaneous measurements of membrane potential, oxidation and phosphorylation rates were perf...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 2014
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2014.05.308